Allergy, Asthma and Immunology

Curriculum Vitae

CLINICAL TRAINING

 2009 - present  Private practice, Ferrell-Duncan Clinic in Springfield, Missouri

 2007 - 2009       Fellow in Allergy and Immunology at Washington University

 2004 - 2006       Resident in Internal Medicine at Barnes-Jewish Hospital in Saint Louis

 2003 - 2004       Intern in Internal Medicine at Barnes-Jewish Hospital in Saint Louis

EDUCATION                                                                                                                                   

 1999 - 2003     M.D., elected member into AOA, Saint Louis University School of  

                           Medicine

 1995 - 1999     Bachelor of Arts, Saint Louis University , Magna Cum Laude

                           Graduated with Honors; major in Biology and minor in Philosophy

RESEARCH EXPERIENCE

 1996 - 2003      Conducted original basic research in Biochemistry and Molecular

                             Biology under Yie-Hwa Chang, Ph.D.

                                 •  Performed research investigating the molecular mechanism of 

                                     angiogenesis and the role of neovascularization in the

                                     pathogenesis  of cancer.

                                 •  Investigated down-stream substrates of the enzyme

                                      Methionine aminopeptidase, the target of the Anti-

                                      angiogenesis compound TNP- 470.

                                 •  Co-invented a dominant negative mutant of type II Methionine

                                      aminopeptidase (patent pending). This genetic construct has

                                      significant potential to serve as a future anti-cancer reagent

                                      as well as assisting in the screening of novel anti-cancer

                                      drugs.

PUBLICATIONS

   Dummitt, B., Micka W.S., Chang, Y.H. Yeast glutamine-fructose-6

           phosphate  aminotransferase (Gfa1) requires methionine aminopeptidase

           activity for proper function. J Biol Chem. 2005 Apr 8;280(14):14356-60. Epub

           2005 Feb 7.

   Vetro, J.A., Dummitt, B., Micka, W.S., Chang, Y.H. Evidence of a dominant negative

           mutant of yeast methionine aminopeptidase type 2 in Saccharomyces

           cerevisiae. J Cell Biochem. 2005 Mar 1;94(4):656-68.

   Dummitt, B., Micka W.S., Chang, Y.H. N-terminal methionine removal and

           methionine metabolism in Saccharomyces cerevisiae. J Cell Biochem. 2003

           Aug 1;89(5):964-74.

ABSTRACTS

    Micka, W.S. , Korenblat, P.E. , An Unusual Complication of Dapsone Therapy. June

            2005.

    Chang, YH, Micka WS and Vetro JA. United States Patent Office Abstract:

           Dominant negative variants of methionine aminopeptidase 2 (MetAP2) and

           clinical uses thereof. Submitted November 13, 2003.
 

AWARDS AND HONORS

    May 2003        Elected into Medical school chapter of AOA

    1999                Recipient of National Science Association Undergraduate Research

                               Grant.

    1999-2003     Achieved Honors in Internal Medicine, Pediatrics,

                               Obstetrics /Gynecology Surgery rotations; Cardiology,

                               Respiratory, Hematology /Lymphatics, Renal,

                               Endocrine, Gastrointestinal, Skin / Connective tissue and        

                               Introduction to Clinical Medicine modules and Cell Biology,

                               Metabolism, Microorganisms and Host response, Pharmacology

                               and Research elective

     May 1999       Graduated Magna Cum Laude with Honors

MEMBERSHIPS

   2007  American Academy of Allergy Asthma and Immunology (AAAAI)

   2007  American College of Allergy Ashthma and Immunology (ACAAI)

VOLUNTEER WORK

   1999-2000     Volunteered at the Medical Student run Health Clinic helping to

                             provide quality, free health care to individuals of North Saint Louis.

    2000             Aided in obtaining donated items from area business for the annual

                             auction to raise funds for the Medical Student Health Clinic.

                             Assisted in planning and organizing the event.